COA Registry › How to read a peptide COA, field by field

COA literacy

How to read a peptide COA, field by field

A COA is a table of claims. Reading one means knowing what each field asserts, what a passing value looks like, and which omissions are disqualifying. Here is the walk-through we use when reviewing submitted certificates.

The nine fields that matter

FieldWhat it assertsWhat to look for
Product nameThe substance and strength testedMatches the label on the vial exactly, including concentration.
Lot numberThe batch these results belong toPresent, specific, and identical to the lot printed on your vial. A COA without a lot number is decorative.
Testing labWho performed the analysisA named laboratory with a real address and phone number — one you can contact. See independent labs.
Test dateWhen analysis happenedA real date, before the release date, not in the future, not years stale.
IdentityThe substance is what the label saysA stated method (commonly HPLC retention match or mass spectrometry) with a pass result.
Potency / assayHow much active ingredient is presentA percentage of label claim with an acceptance range (for example 90–110%). Be suspicious of exactly 100% or values over 100% with no range stated.
SterilityNo microbial growth (injectables)Method referencing USP <71>, result "no growth" / pass.
EndotoxinBacterial endotoxin below limitMethod referencing USP <85>, a numeric result with units (EU/mL or EU/mg) against a stated limit — not just the word "pass".
Beyond-use dateHow long the lot is considered usablePresent and consistent with the test date.

Reading results, not just checkmarks

A trustworthy COA states the method, the specification, and the measured value. "Sterility: pass" with no method reference is weaker than "Sterility (USP <71>): no growth observed at 14 days." Numbers with units and stated acceptance ranges are the signature of a real lab report; bare checkmarks are the signature of a template.

Then verify it

Reading tells you whether the document is coherent. It cannot tell you whether it is authentic — a fabricated COA can be internally perfect. Continue to how to verify a COA and scan the red-flag list.